Mitochondrial DNA Typing Screens with Control Region and Coding Region SNPs
نویسندگان
چکیده
منابع مشابه
Ph . D . Mitochondrial DNA Typing Screens with Control Region and Coding Region SNPs ∗
Mitochondrial DNA (mtDNA) analysis has found an important niche in forensic DNA typing. It is used with highly degraded samples or low-copy number materials such as might be found from shed hair or bones exposed to severe environmental conditions. The primary advantage of mtDNA is that it is present in high copy number within cells and therefore more likely to be recovered from highly degraded ...
متن کاملMitochondrial DNA typing screens with control region and coding region SNPs.
Mitochondrial DNA (mtDNA) analysis has found an important niche in forensic DNA typing. It is used with highly degraded samples or low-copy number materials such as might be found from shed hair or bones exposed to severe environmental conditions. The primary advantage of mtDNA is that it is present in high copy number within cells and therefore more likely to be recovered from highly degraded ...
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Intraspecific and interspecific nucleotide sequence variations of the mtDNA control region (D-loop) were studied with mtDNAs isolated from tissue specimens of more than 1400 sturgeons of nine species: Russian sturgeon Acipenser gueldenstaedtii , Persian sturgeon A. persicus , Siberian sturgeon A. baerii , Amur sturgeon A. schrenkii , Fringebarbel sturgeon A. nudiventris , sterlet A. ruthenus , ...
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The D-loop region is a hot spot for mitochondrial DNA (mtDNA) alterations, containing two hypervariable segments, HVS-I and HVS-II. In order to identify polymorphic sites and potential genetic background accounting for Hypertrophic CardioMyopathy (HCM) disease, the complete non-coding region of mtDNA from 31 unrelated HCM patients and 45 normal controls were sequenced. The sequences were aligne...
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Both the coding and control regions of mitochondrial DNA (mtDNA) play roles in the generation of diabetes; however, no studies have thoroughly reported on the combined diabetogenic effects of variants in the two regions. We determined the mitochondrial haplogroup and the mtDNA sequence of the control region in 859 subjects with diabetes and 1,151 normoglycemic control subjects. Full-length mtDN...
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ژورنال
عنوان ژورنال: Journal of Forensic Sciences
سال: 2005
ISSN: 0022-1198
DOI: 10.1520/jfs2004293